5x01 "Unusual Suspects"
• Robson Square Conference Centre, 600 Robson St.: Baltimore Convention Center
• Dominion Building, 207 West Hastings St., Gastown: Baltimore Guardian newspaper group
5x02 "Redux"
• Yellow Pages/Dominion Directory, 4260 Still Creek Dr., Burnaby: Defense Advanced Research Projects Agency, exterior and lobby [in "Gethsemane," this building is labeled as Department of Defense, Research Division, Sethsburg, Virginia]
• Justice Institute, 715 McBride Blvd., New Westminster: Defense Advanced Research Projects Agency, interior
• Fraserview Bldg, Woodlands Hospital: Defense Advanced Research Projects Agency, hallway
• Open Learning Agency, 4355 Mathissi Pl., Burnaby: Pentagon warehouse
5x03 "Redux II"
• Hastings Park Racecourse, Exhibition Park: Racetrack
• Atrium Inn, 2889 E. Hastings St.: Staircase to assassin's lookout
• 2 Jays Cafe, 81 West Pender Street: Diner, site of the Mulder family reunion
• 400 block of W. Cordova St., Gastown: Downtown Georgetown, site of Mulder's meeting with the Cigarette-Smoking Man
5x04 "Detour"
• Seymour Demonstration Forest, North Vancouver: Route 43, Leon County, Florida and surrounding forest
• Lions Gate Travelodge, 2060 Marine Drive, North Vancouver: Motel (Scully, room 224; Mulder, room 222)
5x05 "Christmas Carol"
• Ortona Cres., Dept. of National Defence (DND) Jericho Base: Bill Scully Residence, U.S. Naval Station, San Diego, California
• 3106 Alberta St.: Sim residence, San Diego
5x06 "Post-Modern Prometheus"
• Muskrat Meadow, Deas Island Regional Park, Delta: Site of peanut butter sandwich trap
• Maplewood Flats Wildlife Sanctuary, 2600 block Dollarton Hwy, North Vancouver: Hillside on property of Farmer Pollidori
• Burrvilla, Deas Island Regional Park, Delta: Dr. Pollidori's House
• Read House, 2981 41B St., Delta: Farmer Pollidori's house and barn
• Post Office, Ladner: Post office
5x07 "Emily"
• Ortona Cres., Dept. of National Defence (DND) Jericho Base: Bill Scully Residence, U.S. Naval Station, San Diego, California
• Glen Hospital, 1036 Salsbury Dr.: Retirement home
5x08 "Kitsunegari"
• Old Boiler Room, George Pearson Hospital, West 57th Ave.: Lorton Penitentiary cafeteria, Washington, D.C.
• Great Outdoors, 201 Lonsdale Ave, North Vancouver: Sporting goods store, Occoquan, Virginia
5x09 "Schizogeny"
• Hazelgrove Farms, Ft. Langley: Hazelnut orchard, Coats Grove, Michigan
5x10 "Chinga"
• Shop Easy, 2535 Shaughnessy St., Port Coquitlam: Supr Savr supermarket, Ammas Beach, Maine
• Marine Dr., White Rock: Main street, Ammas Beach
• Save On Gas, Brooksbank Av., North Vancouver: Gas station, Ammas Beach
• Crescent Beach, White Rock: Wee Lassies and Laddies Daycare
5x11 "Kill Switch"
• Vancouver waterfront: Shipping container lot
• Back lot at BFI Recycling, Burnaby: Shipping container explosion
• Read House, 2981 41B St., Delta: Derelict chicken farm with T3 connection, Fairfax County, Virginia
• Near Boundary Bay Airport: Trailer, Fairfax County
• Westham Island Bridge, Canoe Pass, Delta: Swingspan bridge
5x12 "Bad Blood"
• Tolko Industries site, 200 Bridge Street, North Vancouver: Rolling Acres RV Camp, Cheney, Texas
5x13 "Patient X"
• Gravel Pit, Seymour Demonstration Forest: Forest and clearing, Kazakstan, Former Soviet Union
• Port Mann Substation, 14115 King Road, Surrey: Boiler room, Uroff-Koltoff Star of Russia
• Seymour Demonstration Forest: Skyland Mountain National Park, Virginia
• Outside of psych hospital in Burnaby: Phone booth, Scudder Road, off I-90
• Ruskin Dam, Dewdney Trunk Rd., between Ruskin and Mission: Ruskin Dam, Pennsylvania
5x14 "The Red and the Black"
• Grouse Mountain: CSM's cabin, R. R. # 1, North Hatley, Quebec, Canada
• Ruskin Dam, Dewdney Trunk Rd., between Ruskin and Mission: Ruskin Dam, Pennsylvania
• BC Children's and Women’s Health Centre: Memorial Hospital, Washington, D.C.
• Stokes Pit, South Surrey: UFO crash site, Wiekamp Air Force Base
• BC Parks Works Yard, Base of Seymour Mountain, North Vancouver: Main gate, Wiekamp Air Force Base
5x15 "Travelers"
• 18237-16 Ave., Surrey: Old Man Skur’s rental house, Caledonia, Wisconsin
• The Meatmarket Restaurant, 1 West Cordova Street, Gastown: The Hoot Owl Bar, Washington, D.C.
• Country road near U.S. border, Surrey: Rural road, site of Skur's liberation by Bill Mulder
5x16 "Mind's Eye"
• Blarney Stone Pub, 216 Carrall Street, Gastown: The Blarney Stone Inn, Wilmington, Delaware
• Hastings Park Racecourse, Exhibition Park: French St. Bus Terminal, Wilmington, Delaware
5x17 "All Souls"
• 500 block of East 12th St., North Vancouver: Kernof residence
• St. Augustine's Parish, 2028 West 7th Ave: St. John's Church, Alexandria, Virginia
• Old Boiler Room, George Pearson Hospital, West 57th Ave.: Church of St. Peter the Sinner
• Station Street: Rundown neighborhood, Washington, D.C.
5x18 "Pine Bluff Variant"
• Rose Garden, Stanley Park: Folger Park, Washington, D.C.
• 2400 Court Motel, 2400 Kingsway: Aaron Burr Motor Court, Angola, Delaware (Room 130?)
• Dunbar Theatre, 4555 Dunbar Street: Dunbar Theater, Gables Corner, Ohio
• 1010 Salsbury St.: Mulder's apartment building, 2630 Hegal Place, Alexandria, Virginia, exterior
• Bank of Canada, 900 W. Hastings: First Sovereign Bank of Pennsylvania, Harrisburg, Pennsylvania
5x19 "Folie a Deux"
• 12340 Horseshoe Way, Richmond: VinylRight Corporation, Oak Brook Illinois, exterior
• 1950 Cedar Village Crescent, North Vancouver: Gary Lambert Residence, Oak Brook, Illinois (Apt. 87?)
• 500 block East 11th St., North Vancouver: Starns residence
5x20 "The End"
• General Motors Place, 800 Griffiths Way: Chess tournament, Vancouver, British Columbia
• Riverview Hospital: Federal Detention Facility, Ft. Marlene, Maryland; Ignet Murray Psychiatric Hospital
• Avalon Hotel, 1025 Marine Drive, North Vancouver: Avalon Hotel, site of CSM's encounter with WMM and Kryceck
• London Guard Motel, 2277 Kingsway: Motel, Centerville, Virginia
• Skytrain overpass next to GM Place: Empty lot, site where CSM hands over Gibson